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Clinical Medicine Insights: Blood Disorders 2008:1 21-25
Published on 09 Feb 2008
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Hôpital Saint Louis AP-HP, services d’hématologie et radiothérapie, Paris, France. ²Hôpital Notre Dame, Charleroi, Belgique.
Abstract
In patients with Hodgkin lymphoma (HL) a continued improvement in outcome with a high cure rate is observed but with an increased treatment-induced late effects. We report the long-term results from 188 (stage I to IIIA) patients treated during the period 1985–94 with 3 courses of ABVD-like chemotherapy and subtotal nodal radiotherapy. 10 year overall survival is of 88% and no secondary leukaemia was observed. The main long term toxicity was cardiac, mainly related to a mediastinal dose of 45 Grays in patients with partial remission. New strategies are aiming to reduce the mediastinal dose at 30 Grays after chemotherapy-induced complete remission.
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This is the first time we published an article in Substance Abuse: Research and Treatment, and we were pleased to find that the publishing staff were extremely helpful in guiding our submission through all the hoops. More important they answered our concerns without delay and where necessary made changes in the page proofs in accord with our wishes. I have published upwards of 80 or 90 articles, chapters and edited volumes, and I have ...
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