Levobupivacaine for Regional Anesthesia and Pain Management

Laurence Weinberg; Raymond Hu; Stephanie P. Chen

JOURNAL

Clinical Medicine Reviews in Therapeutics

Levobupivacaine for Regional Anesthesia and Pain Management

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Laurence Weinberg, Raymond Hu and Stephanie P. Chen

Clinical Medicine Reviews in Therapeutics 2011:3 371-397

Review

Published on 28 Sep 2011

DOI: 10.4137/CMRT.S5150

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Abstract

Levobupivacaine is an enantiomer of racemic bupivacaine with a safe pharmacological profile. We present a review of levobupivacaine and its current clinical use in regional anaesthesia and pain management. The pharmacokinetic and pharmacodynamic profile of levobupivacaine is discussed and a qualitative review of studies involving levobupivacaine for regional anaesthesia is presented. Comparisons of levobupivacaine with other local anaesthetic agents as well as studies looking at different doses of levobupivacaine are overviewed.

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