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Substance Abuse: Research and Treatment

Synopsis: An open access, peer reviewed electronic journal that covers all aspects of human substance abuse research and treatment.


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About this journal

ISSN: 1178-2218



Aims and scope:

Substance Abuse: Research and Treatment is an international, open access, peer reviewed journal which considers manuscripts on all areas of human substance abuse research and treatment. These areas include: medical treatment and screening; mental health services; research; and evaluation of substance abuse programs.

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Submissions, excluding editorials, letters to the editor and dedications, will be peer reviewed by two reviewers.  Reviewers are required to provide fair, balanced and constructive reports.  

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Hepatitis Infection in the Treatment of Opioid Dependence and Abuse

Authors: Thomas F. Kresina, Diana Sylvestre, Leonard Seeff, Alain H. Litwin, Kenneth Hoffman, Robert Lubran and H. Westley Clark
Publication Date: 28 Apr 2008
Substance Abuse:Research and Treatment 2008:1 15-61

Thomas F. Kresina1, Diana Sylvestre2, Leonard Seeff3, Alain H. Litwin4, Kenneth Hoffman1, Robert Lubran1 and H. Westley Clark1

1Center for Substance Abuse Treatment, Substance Abuse and Mental Health Services Administration, Rockville, MD. 2Department of Medicine, University of California, San Francisco and Organization to Achieve Solutions In Substance Abuse (O.A.S.I.S.) Oakland, CA. 3Division of Digestive Diseases and Nutrition, National Institute on Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, DHHS, Bethesda, MD. 4Division of Substance Abuse, Albert Einstein College of Medicine, Montefiore Medical Center Bronx, NY.

Abstract

Many new and existing cases of viral hepatitis infections are related to injection drug use. Transmission of these infections can result directly from the use of injection equipment that is contaminated with blood containing the hepatitis B or C virus or through sexual contact with an infected individual. In the latter case, drug use can indirectly contribute to hepatitis transmission through the dis-inhibited at-risk behavior, that is, unprotected sex with an infected partner. Individuals who inject drugs are at-risk for infection from different hepatitis viruses, hepatitis A, B, or C. Those with chronic hepatitis B virus infection also face additional risk should they become co-infected with hepatitis D virus. Protection from the transmission of hepatitis viruses A and B is best achieved by vaccination. For those with a history of or who currently inject drugs, the medical management of viral hepatitis infection comprising screening, testing, counseling and providing care and treatment is evolving. Components of the medical management of hepatitis infection, for persons considering, initiating, or receiving pharmacologic therapy for opioid addiction include: testing for hepatitis B and C infections; education and counseling regarding at-risk behavior and hepatitis transmission, acute and chronic hepatitis infection, liver disease and its care and treatment; vaccination against hepatitis A and B infection; and integrative primary care as part of the comprehensive treatment approach for recovery from opioid abuse and dependence. In addition, participation in a peer support group as part of integrated medical care enhances treatment outcomes. Liver disease is highly prevalent in patient populations seeking recovery from opioid addiction or who are currently receiving pharmacotherapy for opioid addiction. Pharmacotherapy for opioid addiction is not a contraindication to evaluation, care, or treatment of liver disease due to hepatitis virus infection. Successful pharmacotherapy for opioid addiction stabilizes patients and improves patient compliance to care and treatment regimens as well as promotes good patient outcomes. Implementation and integration of effective hepatitis prevention programs, care programs, and treatment regimens in concert with the pharmacological therapy of opioid addiction can reduce the public health burdens of hepatitis and injection drug use.



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Posted by
rizwan
00:50,May 31, 2008

Comprehensive resources for those looking for recovery from addiction. http://addictionrecovery.net

Posted by
Udhaya
16:34,May 29, 2008

Addiction treatment and recovery resources for the addict and their families. http://www.addictiontreatment.net


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