Indian Journal of Clinical Medicine

This case report describes the presentation of new onset of worsening bilateral proximal and distal upper and lower limb weaknesses for the past three months in a 48-year-old man. His past medical history includes only essential hypertension. He denied any fever, diarrhea, or recent vaccination prior to the onset of his symptoms. He had vague patchy sensory loss in both right upper and lower limbs with no clear dermatomal distribution. The magnetic resonance imaging (MRI) of the cervical spine revealed features consistent of partial transverse myelitis. Cerebrospinal fluid (CSF) analysis showed raised opening pressure with evidence of yeast cells on gram stain examination on three different occasions. His neurological symptoms and signs responded to a two-week course of intravenous amphotericin B and oral flucytosine, but there remained minimal residual neurological deficit.