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Cell & Tissue Transplantation & Therapy

Do Mesenchymal Stem Cells Have a Role to Play in Cutaneous Wound Healing?

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Cell & Tissue Transplantation & Therapy 2014:6 11-17

Review

Published on 14 May 2014

DOI: 10.4137/CTTT.S12278


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Abstract

Cutaneous wounds represent a significant healthcare problem despite our increasing understanding of the molecular and cellular events governing this process. A major contributor to this problem is the lack of reliable therapies for the treatment of “hard-to-heal” wounds. Tissue engineering with the use of mesenchymal stem cells (MSCs) have emerged as a promising therapeutic tool with favorable early experimental and clinical results. This manuscript aims to provide an overview of the available approaches to up-regulate the cutaneous wound response with the use of MSCs.



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