Close
Help




JOURNAL

Clinical Medicine Reviews in Vascular Health

Aliskiren-Hydrochlorothiazide in Combination: Efficacy Review in Mild to Moderate Hypertension

Submit a Paper


Clinical Medicine Reviews in Vascular Health 2010:2

Review

Published on 03 Jun 2010

DOI: 10.4137/CMRVH.S4614


Further metadata provided in PDF



Sign up for email alerts to receive notifications of new articles published in Clinical Medicine Reviews in Vascular Health

Abstract

Hypertension is one of the major cardiovascular and renal risk factors and is linked to high morbidity and mortality in patients worldwide. The control rates of hypertensive patients are still low, and this makes the issue of newer drugs highly necessary in order to improve control rates. Since this will be affected by efficacy as well as compliance to antihypertensive medications, we require drugs offering reducing properties against high blood pressure as well as a minimum of adverse effects. The drug class of renin angiotensin system inhibitors is the most-used class for treating hypertension in regard to efficacy as well as tolerability. Recently, a new player in this field was introduced: the direct renin inhibitor aliskiren. Here we review the efficacy and safety of aliskiren alone and in the combination with hydrochlorothiazide, an interesting combination partner since their mode of action allows synergistic effects in regard to lowering blood pressure as well as in reducing possible side effects of both drugs.



Downloads

RIS citation   (ENDNOTE, REFERENCE MANAGER, PROCITE, REFWORKS)

BibTex citation   (BIBDESK, LATEX)


Sharing


What Your Colleagues Say About Clinical Medicine Reviews in Vascular Health
Publishing in Clinical Medicine Reviews in Vascular Health was a pleasant experience. The process was fast and fair. The staff were very professional and we were well informed of the progress of the manuscript.
Dr Abd A Tahrani MD (Birmingham Heartlands Hospital, University of Birmingham, UK)
More Testimonials

Quick Links


New article and journal news notification services
Email Alerts RSS Feeds
Facebook Google+ Twitter
Pinterest Tumblr YouTube