Mencoboni M¹, Bergaglio M², Truini M³, Varaldo M⁴

¹Medical Oncology Unit, “Villa Scassi” Hospital, Genova, Italy. ²Medical Oncology Unit, “Villa Scassi” Hospital, Genova, Italy. ³Pathology Unit, “National Cancer Institute”, Genova, Italy. ⁴Urology Unit, “Villa Scassi” Hospital, Genova, Italy.

Abstract

The case presented here illustrates a 75 year old female patient who underwent surgical resection of a right adrenal mass of uncertain nature. The final histological diagnosis was consistent with leiomyosarcoma arising from the adrenal anatomic site. Primary leiomyosarcoma of the adrenal gland is a very rare malignant mesenchymal neoplasm: to our knowledge, this is only the twelfth case reported in literature. We describe the clinical course and a brief review of clinical and histological features, biologic behaviour, diagnostic approaches and therapeutic strategies.