Bioinformatics and Biology Insights

Homology-Based Prediction of Potential Protein–Protein Interactions between Human Erythrocytes and Plasmodium falciparum
Gayatri Ramakrishnan, Narayanaswamy Srinivasan, Ponnan Padmapriya and Vasant Natarajan
Bioinformatics and Biology Insights 2015:9 195-206
Original Research | Published on 20 Dec 2015

Sequence Analysis and Evolutionary Studies of Reelin Proteins
Malini Manoharan, Sayyed Auwn Muhammad, and Ramanathan Sowdhamini
Bioinformatics and Biology Insights 2015:9 187-193
Original Research | Published on 20 Dec 2015

DDA: A Novel Network-Based Scoring Method to Identify Disease–Disease Associations
Apichat Suratanee and Kitiporn Plaimas
Bioinformatics and Biology Insights 2015:9 175-186
Original Research | Published on 08 Dec 2015

A Computational Pipeline for Cross-Species Analysis of RNA-seq Data Using R and Bioconductor
Peter R. LoVerso and Feng Cui
Bioinformatics and Biology Insights 2015:9 165-174
Original Research | Published on 02 Dec 2015

Cross-species Transcriptomic Comparison of In Vitro and In Vivo Mammalian Neural Cells
Peter R. LoVerso, Christopher M. Wachter and Feng Cui
Bioinformatics and Biology Insights 2015:9 153-164
Original Research | Published on 25 Nov 2015

Advanced Applications of RNA Sequencing and Challenges
Yixing Han, Shouguo Gao, Kathrin Muegge, Wei Zhang and Bing Zhou
Bioinformatics and Biology Insights 2015:Suppl. 1 29-46
Review | Published on 15 Nov 2015

Development and Application of a Genetic Algorithm for Variable Optimization and Predictive Modeling of Five-Year Mortality Using Questionnaire Data
Lucas J. Adams, Ghalib Bello and Gerard G. Dumancas
Bioinformatics and Biology Insights 2015:Suppl. 3 31-41
Original Research | Published on 08 Nov 2015

Gene Coexpression Networks in Human Brain Developmental Transcriptomes Implicate the Association of Long Noncoding RNAs with Intellectual Disability
Brian L. Gudenas and Liangjiang Wang
Bioinformatics and Biology Insights 2015:Suppl. 1 21-27
Original Research | Published on 27 Oct 2015

Application of Functional Genomics for Bovine Respiratory Disease Diagnostics
Aswathy N. Rai, William B. Epperson and Bindu Nanduri
Bioinformatics and Biology Insights 2015:Suppl. 2 13-23
Review | Published on 22 Oct 2015

Machine Learning Methods for Predicting HLA–Peptide Binding Activity
Heng Luo, Hao Ye, Hui Wen Ng, Leming Shi, Weida Tong, Donna L. Mendrick and Huixiao Hong
Bioinformatics and Biology Insights 2015:Suppl. 3 21-29
Review | Published on 11 Oct 2015 | Video abstract

The Genetic Architecture of Domestication in Animals
Dominic Wright
Bioinformatics and Biology Insights 2015:Suppl. 4 11-20
Commentary | Published on 11 Oct 2015

B-Cell and Monocyte Contribution to Systemic Lupus Erythematosus Identified by Cell-Type-Specific Differential Expression Analysis in RNA-Seq Data
Mikhail G. Dozmorov, Nicolas Dominguez, Krista Bean, Susan R. Macwana, Virginia Roberts, Edmund Glass, Judith A. James and Joel M. Guthridge
Bioinformatics and Biology Insights 2015:Suppl. 3 11-19
Original Research | Published on 08 Oct 2015

Genetics of Prion Disease in Cattle
Brenda M. Murdoch and Gordon K. Murdoch
Bioinformatics and Biology Insights 2015:Suppl. 4 1-10
Review | Published on 24 Sep 2015

The Widening Gulf between Genomics Data Generation and Consumption: A Practical Guide to Big Data Transfer Technology
Frank A. Feltus, Joseph R. Breen III, Juan Deng, Ryan S. Izard, Christopher A. Konger, Walter B. Ligon III, Don Preuss and Kuang-Ching Wang
Bioinformatics and Biology Insights 2015:Suppl. 1 9-19
Review | Published on 23 Sep 2015 | Video abstract

PPCheck: A Webserver for the Quantitative Analysis of Protein–Protein Interfaces and Prediction of Residue Hotspots
Anshul Sukhwal and Ramanathan Sowdhamini
Bioinformatics and Biology Insights 2015:9 141-151
Original Research | Published on 21 Sep 2015

Molecular Dynamics Approach in the Comparison of Wild-Type and Mutant Paraoxonase-1 Apoenzyme Form
Khadija Amine, Lamia Miri, Adil Naimi, Rachid Saile, Abderrahmane El Kharrim, Afaf Mikou and Anass Kettani
Bioinformatics and Biology Insights 2015:9 129-140
Original Research | Published on 13 Sep 2015

BioImg.org: A Catalog of Virtual Machine Images for the Life Sciences
Martin Dahlö, Frédéric Haziza, Aleksi Kallio, Eija Korpelainen, Erik Bongcam-Rudloff and Ola Spjuth
Bioinformatics and Biology Insights 2015:9 125-128
Technical Advance | Published on 10 Sep 2015

Development and Validation of a Clinical Risk-Assessment Tool Predictive of All-Cause Mortality
Ghalib A. Bello, Gerard G. Dumancas and Chris Gennings
Bioinformatics and Biology Insights 2015:Suppl. 3 1-10
Original Research | Published on 01 Sep 2015

Antigenic Determinants of Possible Vaccine Escape by Porcine Circovirus Subtype 2b Viruses
Megan Constans, Marvin Ssemadaali, Oleksandr Kolyvushko and Sheela Ramamoorthy
Bioinformatics and Biology Insights 2015:Suppl. 2 1-12
Original Research | Published on 23 Aug 2015 | Video abstract

A Simple Rank Product Approach for Analyzing Two Classes
Tae Young Yang
Bioinformatics and Biology Insights 2015:9 119-123
Methodology | Published on 16 Jul 2015

High-Throughput miRNA Sequencing Reveals a Field Effect in Gastric Cancer and Suggests an Epigenetic Network Mechanism
Monica B. Assumpção, Fabiano C. Moreira, Igor G. Hamoy, Leandro Magalhães, Amanda Vidal, Adenilson Pereira, Rommel Burbano, André Khayat, Artur Silva, Sidney Santos, Samia Demachki, Ândrea Ribeiro-dos-Santos, and Paulo Assumpção
Bioinformatics and Biology Insights 2015:9 111-117
Original Research | Published on 06 Jul 2015

Prediction of O-glycosylation Sites Using Random Forest and GA-Tuned PSO Technique
Hebatallah Hassan, Amr Badr and M. B. Abdelhalim
Bioinformatics and Biology Insights 2015:9 103-109
Original Research | Published on 05 Jul 2015

High-Throughput Sequencing of miRNAs Reveals a Tissue Signature in Gastric Cancer and Suggests Novel Potential Biomarkers
Sylvain Darnet, Fabiano C Moreira, Igor G Hamoy, Rommel Burbano, André Khayat, Aline Cruz, Leandro Magalhães, Artur Silva, Sidney Santos, Samia Demachki, Monica Assumpção, Paulo Assumpção, and Ândrea Ribeiro-dos-Santos
Bioinformatics and Biology Insights 2015:Suppl. 1 1-8
Original Research | Published on 28 Jun 2015

Computational and in vitro Investigation of miRNA-Gene Regulations in Retinoblastoma Pathogenesis: miRNA Mimics Strategy
Nalini Venkatesan, Perinkulam Ravi Deepa, Vikas Khetan and Subramanian Krishnakumar
Bioinformatics and Biology Insights 2015:9 89-101
Original Research | Published on 12 May 2015

Metagenomics: Tools and Insights for Analyzing Next-Generation Sequencing Data Derived from Biodiversity Studies
Anastasis Oulas, Christina Pavloudi, Paraskevi Polymenakou, Georgios A. Pavlopoulos, Nikolas Papanikolaou, Georgios Kotoulas, Christos Arvanitidis and Ioannis Iliopoulos
Bioinformatics and Biology Insights 2015:9 75-88
Review | Published on 05 May 2015

Reverse enGENEering of Regulatory Networks from Big Data: A Roadmap for Biologists
Xiaoxi Dong, Anatoly Yambartsev, Stephen A. Ramsey, Lina D Thomas, Natalia Shulzhenko and Andrey Morgun
Bioinformatics and Biology Insights 2015:9 61-74
Review | Published on 29 Apr 2015

Cross-Disciplinary Detection and Analysis of Network Motifs
Ngoc Tam L. Tran, Luke DeLuccia, Aidan F. McDonald and Chun-Hsi Huang
Bioinformatics and Biology Insights 2015:9 49-60
Original Research | Published on 19 Apr 2015

An Interpretation of the Ancestral Codon from Miller's Amino Acids and Nucleotide Correlations in Modern Coding Sequences
Nicolas Carels and Miguel Ponce de Leon
Bioinformatics and Biology Insights 2015:9 37-47
Original Research | Published on 15 Apr 2015

A Systems Biology Approach Reveals the Dose- and Time-Dependent Effect of Primary Human Airway Epithelium Tissue Culture After Exposure to Cigarette Smoke In Vitro
Carole Mathis, Stephan Gebel, Carine Poussin, Vincenzo Belcastro, Alain Sewer, Dirk Weisensee, Arnd Hengstermann, Sam Ansari, Sandra Wagner, Manuel C. Peitsch and Julia Hoeng
Bioinformatics and Biology Insights 2015:9 19-35
Original Research | Published on 09 Mar 2015

Identification and Expression Analysis of Ribosome Biogenesis Factor Co-orthologs in Solanum lycopersicum
Stefan Simm, Sotirios Fragkostefanakis, Puneet Paul, Mario Keller, Jens Einloft, Klaus-Dieter Scharf and  Enrico Schleiff
Bioinformatics and Biology Insights 2015:9 1-17
Original Research | Published on 09 Feb 2015

POEAS: Automated Plant Phenomic Analysis Using Plant Ontology
Khader Shameer, Mahantesha BN Naika, Oommen K. Mathew, and Ramanathan Sowdhamini
Bioinformatics and Biology Insights 2014:8 209-214
Original Research | Published on 21 Dec 2014

Computational Methods for CLIP-seq Data Processing
Paula H. Reyes-Herrera and Elisa Ficarra
Bioinformatics and Biology Insights 2014:8 199-207
Review | Published on 01 Oct 2014

Interactions Among Plant Transcription Factors Regulating Expression of Stress-responsive Genes
Sony Malhotra and R. Sowdhamini
Bioinformatics and Biology Insights 2014:8 193-198
Original Research | Published on 10 Sep 2014

Integrated Analysis of Dysregulated miRNA-gene Expression in HMGA2-silenced Retinoblastoma Cells
Nalini Venkatesan, PR Deepa, Madavan Vasudevan, Vikas Khetan, Ashwin M Reddy and Subramanian Krishnakumar
Bioinformatics and Biology Insights 2014:8 177-191
Original Research | Published on 04 Sep 2014

Computational Identification of Dengue Virus MicroRNA-Like Structures and their Cellular Targets
Maicol Ospina-Bedoya, Natalia Campillo-Pedroza, Juan P. Franco-Salazar and Juan C. Gallego-Gómez
Bioinformatics and Biology Insights 2014:8 169-176
Short Report | Published on 14 Aug 2014

In Silico Studies of Medicinal Compounds Against Hepatitis C Capsid Protein from North India
Shilu Mathew, Muhammad Faheem, Govindaraju Archunan, Muhammad Ilyas, Nargis Begum, Syed Jahangir, Ishtiaq Qadri, Mohammad Al Qahtani and Shiny Mathew
Bioinformatics and Biology Insights 2014:8 159-168
Original Research | Published on 23 Jun 2014

Identification of Chicken Pulmonary miRNAs Targeting PB1, PB1-F2, and N40 Genes of Highly Pathogenic Avian Influenza Virus H5N1 In Silico
Amod Kumar, Muhasin Asaf V.N., Ashwin Ashok Raut, Richa Sood and Anamika Mishra
Bioinformatics and Biology Insights 2014:8 135-145
Original Research | Published on 12 Jun 2014

DOR – a Database of Olfactory Receptors – Integrated Repository for Sequence and Secondary Structural Information of Olfactory Receptors in Selected Eukaryotic Genomes
Balasubramanian Nagarathnam, Snehal D. Karpe, Krishnan Harini, Kannan Sankar, Mohammed Iftekhar, Durairaj Rajesh, Sadasivam Giji, Govidaraju Archunan, Veluchamy Balakrishnan, M. Michael Gromiha, Wataru Nemoto, Kazhuhiko Fukui and Ramanathan Sowdhamini
Bioinformatics and Biology Insights 2014:8 147-158
Original Research | Published on 12 Jun 2014

A Protocol for mtGenome Analysis on Large Sample Numbers
Igor G. Hamoy, André M. Ribeiro-dos-Santos, Luiz Alvarez, Silvanira Barbosa, Artur Silva, Sidney Santos, Leonor Gusmão and Ândrea Ribeiro-dos-Santos
Bioinformatics and Biology Insights 2014:8 127-134
Original Research | Published on 11 Jun 2014

High-throughput Methods Redefine the Rumen Microbiome and Its Relationship with Nutrition and Metabolism
Joshua C. McCann, Tryon A. Wickersham and Juan J. Loor
Bioinformatics and Biology Insights 2014:8 109-125
Review | Published on 08 Jun 2014

The Purine Bias of Coding Sequences is Determined by Physicochemical Constraints on Proteins
Miguel Ponce de Leon, Antonio Basilio de Miranda, Fernando Alvarez-Valin and Nicolas Carels
Bioinformatics and Biology Insights 2014:8 93-108
Original Research | Published on 20 May 2014

Promise and Reality in the Expanding Field of Network Interaction Analysis: Metabolic Networks
Susanna Bazzani
Bioinformatics and Biology Insights 2014:8 83-91
Commentary | Published on 16 Apr 2014

Computational Insights of the Interaction among Sea Anemones Neurotoxins and Kv1.3 Channel
Angélica Sabogal-Arango, George E. Barreto, David Ramírez-Sánchez, Juan González-Mendoza, Viviana Barreto, Ludis Morales and Janneth González
Bioinformatics and Biology Insights 2014:8 73-81
Original Research | Published on 15 Apr 2014

An In Silico Approach for Characterization of an Aminoglycoside Antibiotic-Resistant Methyltransferase Protein from Pyrococcus furiosus (DSM 3638)
Arafat Rahman Oany, Tahmina Pervin Jyoti and Shah Adil Ishtiyaq Ahmad
Bioinformatics and Biology Insights 2014:8 65-72
Original Research | Published on 20 Mar 2014

Postpartal Subclinical Endometritis Alters Transcriptome Profiles in Liver and Adipose Tissue of Dairy Cows
Haji Akbar, Felipe C. Cardoso, Susanne Meier, Christopher Burke, Scott McDougall, Murray Mitchell, Caroline Walker, Sandra L. Rodriguez-Zas, Robin E. Everts, Harris A. Lewin, John R. Roche and Juan J. Loor
Bioinformatics and Biology Insights 2014:8 45-63
Original Research | Published on 19 Feb 2014

Probing the Unknowns in Cytokinin-Mediated Immune Defense in Arabidopsis with Systems Biology Approaches
Muhammad Naseem, Meik Kunz and Thomas Dandekar
Bioinformatics and Biology Insights 2014:8 35-44
Methodology | Published on 13 Feb 2014

Longitudinal Analysis of Whole Blood Transcriptomes to Explore Molecular Signatures Associated With Acute Renal Allograft Rejection
Heesun Shin, Oliver Günther, Zsuzsanna Hollander, Janet E. Wilson-McManus, Raymond T. Ng, Robert Balshaw, Paul A. Keown, Robert McMaster, Bruce M. McManus, Nicole M. Isbel, Greg Knoll and Scott J. Tebbutt; for the PROOF Centre of Excellence Team
Bioinformatics and Biology Insights 2014:8 17-33
Original Research | Published on 22 Jan 2014

GeneSV – an Approach to Help Characterize Possible Variations in Genomic and Protein Sequences
Adam Zemla, Tanya Kostova, Rodion Gorchakov, Evgeniya Volkova, David W. C. Beasley, Jane Cardosa, Scott C. Weaver, Nikos Vasilakis and Pejman Naraghi-Arani
Bioinformatics and Biology Insights 2014:8 1-16
Original Research | Published on 08 Jan 2014

Three Dimensional Structure Prediction of Fatty Acid Binding Site on Human Transmembrane Receptor CD36
Zineb Tarhda, Oussama Semlali, Anas Kettani, Ahmed Moussa, Nada A. Abumrad and Azeddine Ibrahimi
Bioinformatics and Biology Insights 2013:7 369-373
Original Research | Published on 02 Dec 2013

ChIP-Seq Data Mining: Remarkable Differences in NRSF/REST Target Genes between Human ESC and ESC-Derived Neurons
Jun-ichi Satoh, Natsuki Kawana and Yoji Yamamoto
Bioinformatics and Biology Insights 2013:7 357-368
Original Research | Published on 01 Dec 2013