Leptomeningeal Metastases in a Patient with an Extragonadal Germ Cell Tumor
Yoshiaki Kinebuchi1, Masakuni Ishikawa1, Osamu Ishizuka1, Osamu Nishizawa1 and Kazuhiro Hongo2
1Departments of Urology and 2Neurosurgery, Shinshu University School of Medicine, Matsumoto, Japan.
Abstract
We present a case of leptomeningeal metastases in a 30-year-old man with an extragonadal germ cell tumor. The patient was referred to our hospital for treatment of an occipital brain metastasis. This lesion was resected, followed by whole brain radiotherapy and further chemotherapy, and a temporary complete remission was achieved. However, leptomeningeal recurrence developed, and despite salvage chemotherapy, the patient died of disease. Although multidisciplinary treatment is given to treat brain metastases of germ cell tumors, the patients’ prognosis has been unsatisfactory. The identification of a standard/effective treatment is required.
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