@article{10.4137/CMO.S13241, author={Bhavna Gami and Faris Kubba and Paul Ziprin}, journal={Clinical Medicine Insights: Oncology}, publisher={Libertas Academica}, title={Human Papilloma Virus and Squamous Cell Carcinoma of the Anus}, year={2014}, month={09}, volume={8}, url={www.la-press.com/human-papilloma-virus-and-squamous-cell-carcinoma-of-the-anus-article-a4384}, pages={113--119}, abstract={ The incidence of anal cancer is increasing. In the UK, the incidence is estimated at approximately 1.5 per 100,000. Most of this increase is attributed to certain at-risk populations. Persons who are human immunodeficiency virus (HIV)–positive and men who have sex with men (MSM), Organ transplant recipients, women with a history of cervical cancer, human papilloma virus (HPV), or cervical intraepithelial neoplasia (CIN) are known to have a greater risk for anal cancer. This paper will focus on HPV as a risk factor for anal intraepithelial neoplasia (AIN) and discusses the etiology, anatomy, pathogenesis, management of squamous cell carcinoma (SCC) of the anus. }, doi={10.4137/CMO.S13241}, }