Perspectives in Medicinal Chemistry

Applications of Second-Harmonic Generation Imaging Microscopy in Ovarian and Breast Cancer (Published on 16 Apr 2015)

Download Full Open Access Article in PDF Format (2.31 MB)

Selective Mycobacterium tuberculosis Shikimate Kinase Inhibitors as Potential Antibacterials (Published on 15 Mar 2015)

Download Full Open Access Article in PDF Format (2.01 MB)

New Approaches to Treating Alzheimer’s Disease (Published on 09 Feb 2015)

Download Full Open Access Article in PDF Format (647.63 KB)

Antimicrobial Peptides and Their Analogs: Searching for New Potential Therapeutics (Published on 12 Oct 2014)

Download Full Open Access Article in PDF Format (639.03 KB)

Multiple Sclerosis: Overview of Disease-Modifying Agents (Published on 05 Oct 2014)

Download Full Open Access Article in PDF Format (458.88 KB)

Antibiotics and Bacterial Resistance in the 21st Century (Published on 28 Aug 2014)

Download Full Open Access Article in PDF Format (16.28 MB)

Pathways for Small Molecule Delivery to the Central Nervous System Across the Blood-Brain Barrier (Published on 16 Jun 2014)

Download Full Open Access Article in PDF Format (2.48 MB)

Corrigendum for “Stereocomplexes Formed From Select Oligomers of Polymer D-lactic Acid (PDLA) and L-lactate May Inhibit Growth of Cancer Cells and Help Diagnose Aggressive Cancers—Applications of the Warburg Effect” (Published on 25 May 2014)

Download Full Open Access Article in PDF Format (291.61 KB)

Revisiting the Monoamine Hypothesis of Depression: A New Perspective (Published on 03 Apr 2014)

Download Full Open Access Article in PDF Format (901.52 KB)

Low Molecular Weight Opioid Peptide Esters Could be Developed as a New Class of Analgesics (Published on 25 Jul 2011)

Download Full Open Access Article in PDF Format (522.71 KB)

Choroidal Proteins Involved in Cerebrospinal Fluid Production may be Potential Drug Targets for Alzheimer’s Disease Therapy (Published on 23 Feb 2011)

Download Full Open Access Article in PDF Format (507.28 KB)

Stereocomplexes Formed From Select Oligomers of Polymer d-lactic Acid (PDLA) and l-lactate May Inhibit Growth of Cancer Cells and Help Diagnose Aggressive Cancers—Applications of the Warburg Effect (Published on 15 Feb 2011)

Download Full Open Access Article in PDF Format (642.94 KB)

Selected Gamma Aminobutyric Acid (GABA) Esters may Provide Analgesia for Some Central Pain Conditions (Published on 03 Aug 2010)

Download Full Open Access Article in PDF Format (562.23 KB)

Fentanyl Buccal Tablet for the Treatment of Breakthrough Pain: Pharmacokinetics of Buccal Mucosa Delivery and Clinical Efficacy (Published on 04 Jun 2010)

Download Full Open Access Article in PDF Format (705.56 KB)

Stereochemical Basis for a Unified Structure Activity Theory of Aromatic and Heterocyclic Rings in Selected Opioids and Opioid Peptides (Published on 18 Feb 2010)

Download Full Open Access Article in PDF Format (1.71 MB)

Chaperone Therapy for Neuronopathic Lysosomal Diseases: Competitive Inhibitors as Chemical Chaperones for Enhancement of Mutant Enzyme Activities (Published on 26 May 2009)

Download Full Open Access Article in PDF Format (1.33 MB)

Aminoglycosides: Molecular Insights on the Recognition of RNA and Aminoglycoside Mimics (Published on 28 Apr 2009)

Download Full Open Access Article in PDF Format (1.61 MB)

Perspectives on Using Physcomitrella  Patens as an Alternative Production Platform for Thapsigargin and Other Terpenoid Drug Candidates (Published on 04 Mar 2009)

Download Full Open Access Article in PDF Format (515.87 KB)

Bioactive and Structural Metabolites of Pseudomonas and Burkholderia Species Causal Agents of Cultivated Mushrooms Diseases (Published on 09 May 2008)

Download Full Open Access Article in PDF Format (3.13 MB)

The Role of Integrins in Cancer and the Development of Anti-Integrin Therapeutic Agents for Cancer Therapy (Published on 10 Apr 2008)

Download Full Open Access Article in PDF Format (500.06 KB)

Drug Targeting of α-Synuclein Oligomerization in Synucleinopathies (Published on 10 Apr 2008)

Download Full Open Access Article in PDF Format (480.27 KB)

Lunasin: A Novel Cancer Preventive Seed Peptide (Published on 25 Mar 2008)

Download Full Open Access Article in PDF Format (361.07 KB)

Effects of FK506 on Ca2+ Release Channels (Review) (Published on 18 Mar 2008)

Download Full Open Access Article in PDF Format (230.87 KB)

Small Family with Key Contacts: Par14 and Par17 Parvulin Proteins, Relatives of Pin1, Now Emerge in Biomedical Research (Published on 07 Mar 2008)

Download Full Open Access Article in PDF Format (1.73 MB)

Modifications of Antiepileptic Drugs for Improved Tolerability and Efficacy (Published on 14 Feb 2008)

Download Full Open Access Article in PDF Format (557.07 KB)

Exploratory Studies on Development of the Chemokine Receptor CXCR4 Antagonists Toward Downsizing (Published on 10 Feb 2008)

Download Full Open Access Article in PDF Format (334.99 KB)

The Role of Glucose Metabolism and Glucose-Associated Signalling in Cancer (Published on 18 Jan 2008)

Download Full Open Access Article in PDF Format (510.80 KB)

Chemical Chaperone and Inhibitor Discovery: Potential Treatments for Protein Conformational Diseases (Published on 11 Dec 2007)

Download Full Open Access Article in PDF Format (346.31 KB)

Derivatives of 5-Aminolevulinic Acid for Photodynamic Therapy (Published on 11 Dec 2007)

Download Full Open Access Article in PDF Format (301.16 KB)

The pKa Distribution of Drugs: Application to Drug Discovery (Published on 17 Sep 2007)

Download Full Open Access Article in PDF Format (421.03 KB)

FTY720 Story. Its Discovery and the Following Accelerated Development of Sphingosine 1-Phosphate Receptor Agonists as Immunomodulators Based on Reverse Pharmacology (Published on 06 Sep 2007)

Download Full Open Access Article in PDF Format (571.69 KB)

Lead Optimization in Discovery Drug Metabolism and Pharmacokinetics/Case study: The Hepatitis C Virus (HCV) Protease Inhibitor SCH 503034 (Published on 26 Jun 2007)

Download Full Open Access Article in PDF Format (331.15 KB)